With de novo sequencing, the first genome map for a species is generated, providing a valuable reference sequence for phylogenetic studies, analysis of species diversity, mapping of specific traits and genetic markers, and other genomics research.
Novogene is at the forefront of de novo sequencing as it becomes more rapid and affordable. Novogene’s founder, Dr. Ruiqiang Li, is a leading genomics expert and a primary developer of the SOAPdenovo software package for genome assembly. Dr. Li and the Novogene team have contributed to many important publications on novel genome sequences, and we can provide you with the high level of expertise required for your specific project.
With the addition of 20 latest PacBio Sequel Systems that provide long range sequencing and seven times higher throughput, Novogene has become the world’s largest PacBio SMRT sequencing facility. Novogene offers de novo sequencing service using various platforms including PacBio Sequel, Illumina HiSeq, and 10X Genomics Chromium platforms. For each project, our scientists will design the best sequencing strategy utilizing an optimal combination of short reads and long range sequence information to achieve the most comprehensive de novo assembly results for your genome of interest.
Simple genome refers to a haploid genome with a low repeat content (less than 50%), or a diploid genome with a low rate of heterozygosity (less than 0.5%), such as most mammals, birds, and cultivated crops.
Complex genome refers to a diploid or polyploid genome with a high repeat content (higher than 50%) or a high rate of heterozygosity (higher than 0.5%), such as many species of plants, aquatics, and insects.
- Moderately heterozygous genome (diploid)
- Highly heterozygous genome (diploid)
- Highly repetitive genome (diploid)